L-Glutathione(Oxidized Form)
Oxiglutatione
CAS: 27025-41-8
Molecular Formula: C20H32N6O12S2
L-Glutathione(Oxidized Form) - Names and Identifiers
| Name | Oxiglutatione |
| Synonyms | NOV-002 Oxiglutatione glutathione-ssg l(-)-Glutathione White lyophilizate oxidizedglutathione glutathonedisulfide glutathionedisulphide Glutathione disulfide l-oxidizedglutathione L-Glutathione(Oxidized Form) Glutathione(Oxidized Form), free acid n-(n-gamma-glutamyl-cysteinyl)glycine-(2,2)-disulfide N-(N-.gamma.-Glutamyl-cysteinyl)glycine-2,2-disulfide Glycine,L-.gamma.-glutamyl-L-cysteinyl-,2,2'-disulfide glycine,l-gamma-glutamyl-l-cysteinyl-,(2,2')-disulfide n'-(dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-l-glutamin N,N'-[dithiobis[1-[(carboxymethyl)carbamoyl]ethylene]]di-,L-Glutamine 5,5'-[disulfanediylbis({3-[(carboxymethyl)amino]-3-oxopropane-1,2-diyl}imino)]bis(2-amino-5-oxopentanoic acid) (non-preferred name) (2S,2'S)-5,5'-[disulfanediylbis({(2R)-3-[(carboxymethyl)amino]-3-oxopropane-1,2-diyl}imino)]bis(2-amino-5-oxopentanoic acid) (non-preferred name) |
| CAS | 27025-41-8 |
| EINECS | 248-170-7 |
| InChI | InChI=1/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1 |
| InChIKey | YPZRWBKMTBYPTK-USZNOCQGSA-N |
L-Glutathione(Oxidized Form) - Physico-chemical Properties
| Molecular Formula | C20H32N6O12S2 |
| Molar Mass | 612.63 |
| Density | 1.3688 (rough estimate) |
| Melting Point | 178°C (dec.)(lit.) |
| Boling Point | 1196.5°C at 760 mmHg |
| Specific Rotation(α) | -99 º (c=4, water) |
| Flash Point | 677.4°C |
| Water Solubility | soluble |
| Solubility | Soluble in water, insoluble in ethanol and ether |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White to off-white (Solid) |
| Color | White to off-white |
| Merck | 13,4488 |
| BRN | 1718700 |
| pKa | 2.12, 3.59, 8.75, 9.65(at 25℃) |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | -105 ° (C=2, H2O) |
| MDL | MFCD00063106 |
| Physical and Chemical Properties | Melting point 178-182°C specific optical rotation -99 ° (c = 4, water) water-soluble solution |
L-Glutathione(Oxidized Form) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 2 |
| RTECS | MC0556500 |
| HS Code | 29309090 |
L-Glutathione(Oxidized Form) - Reference
| Reference Show more | 1. Song Renyuan, Hu Xiaoling, Guan Ping, et al. Preparation and adsorption properties of glutathione molecularly imprinted polymers by Iniferter radical polymerization [J]. Journal of Chemical Engineering of higher education, 2016, 30(003):641-647. 2. Du Bowei, Xu Xiaobing, Guo Shangwei, etc. Study on small molecule donkey-hide gelatin with high antioxidant activity [J]. Journal of Beijing University of Chemical Technology: natural science, 2019, 46(6):15-20. 3. Li Wei, Chen Liang, Yin dan, Yang Hao, Zhou Jia-Yi, Song Yu, Zhang Yan, Zou Liang. Preparation of tetramethylpyrazine Ophthalmic liposome thermosensitive gel and evaluation of its properties in vitro and in vivo [J]. China Pharmacy, 2021,32(03):320-327. 4. Deng Zhang Shuang, Huang Rong, Liu Xiu-ji, Li Zhihong, Yao Min, Li Xiao, Du Wei-Li, Zou Kun, Gong Dachun. Stability of reduced glutathione produced by yeast during preparation [J]. Journal of China Three Gorges University (natural sciences),2020,42(06):97-102. 5. Li, Xueyuan, et al. "Dual enhanced electroculture of aminated Au @ SiO2/CdS quantum dot superstructures: electromagnetic field enhancement and chemical enhancement." ACS applied materials & interfaces 11.4 (2019): 4488-4499.https:// doi.org/10.1021 6. [IF = 9.776] Qing Pei et al."Paclitaxel dimers assembling nanomedicines for treatment of cervix carcinoma."J Control Release. 2017 May;254:23 7. [IF=9.229] Xueyuan Li et al."Dual Enhanced Electrochemiluminescence of Aminated Au@SiO2/CdS Quantum Dot Superstructures: Electromagnetic Field Enhancement and Chemical Enhancement."Acs Appl Mater Inter. 2019;11(4):4488-4499 8. [IF=8.456] Wenhai Lin et al."Rational Design of Polymeric Nanoparticles with Tailorable Biomedical Functions for Cancer Therapy."Acs Appl Mater Inter. 2017;9(35):29612-29622 9. [IF=6.331] Jianxu Zhang et al."GSH-triggered size increase of porphyrin-containing nanosystems for enhanced retention and photodynamic activity."J Mater Chem B. 2017 Jun;5(23):4470-4477 10. [IF=11.413] Zhenhao Tian et al."A NIR fluorescent probe for Vanin-1 and its applications in imaging kidney injury diagnosis, and the development of inhibitor."Acta Pharm Sin B. 2021 Jun;: 11. [IF=6.023] Ying Liu et al."Mechanistic study of bergamottin-induced inactivation of CYP2C9."Food Chem Toxicol. 2021 Jul;153:112278 12. [IF=4.204] Zhu Mingyue et al."A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living cells and tissues."Frontiers of Chemical Science and Engineering. 2021 Jun 29 13. [IF=4.098] Ting Zhou et al."Fluorescence detections of hydrogen peroxide and glucose with polyethyleneimine-capped silver nanoclusters."Spectrochim Acta A. 2021 Jan;244:118881 |
L-Glutathione(Oxidized Form) - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | L-glutathione can be used as a biomarker for fatty liver. scientific research, experiments, enzymatic determination of hydrogen receptors of NADP and NADPH. |
| biological activity | Oxiglutatione (Oxidized glutathione, Glutathione disulfide, GSSG, Bi(glutathion-S-yl)) is an oxidized disulfide form of glutathione with potential protective activity. |
Last Update：2024-04-10 22:29:15
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